Step 1:

Choose a location from which all wiring will be run from. This is the location that will house your system, media server, tuners etc. You will need an AC outlet, good ventilation, a home run of two RG6 wires to the roof for the tuner antennas, and a connection to the internet for radio stations and album art etc.

Step2:

Run a Cat5e wire to each location where you will have a controller or a music keypad. If you want to have an intercom as well, run an additional Cat5e. Run a 16/4 high strand audio wire alongside, leave a service loop at the keypad area and then continue to the in wall or in ceiling locations of your speakers.

Step3:

Make sure to mark your wires, to avoid running alongside electrical high voltage wiring.

Voila, you should be prepared for the amazing experience of a distributed audio system.